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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
9.7
Human Site:
S875
Identified Species:
21.33
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S875
V
K
T
E
R
D
E
S
S
G
P
K
T
L
K
Chimpanzee
Pan troglodytes
XP_526066
929
104074
E634
H
D
P
M
K
Q
W
E
V
T
S
R
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
D894
E
W
I
S
I
D
K
D
E
A
G
A
K
S
K
Dog
Lupus familis
XP_542327
1264
138869
D900
E
W
I
S
I
D
K
D
E
A
G
A
K
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
S878
V
K
T
E
R
D
E
S
S
G
M
K
C
L
K
Rat
Rattus norvegicus
P97573
1190
133575
S877
V
K
T
E
R
D
E
S
S
G
M
K
C
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
S724
G
R
D
Y
R
E
S
S
E
L
P
H
H
G
K
Chicken
Gallus gallus
XP_422567
1182
133482
I874
V
K
I
E
R
D
E
I
A
G
Q
K
P
K
N
Frog
Xenopus laevis
Q6P4S2
1019
115278
A724
G
D
S
G
D
L
E
A
Q
G
H
I
E
L
M
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
D878
E
W
I
S
V
D
K
D
D
M
G
G
P
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
F880
K
T
Y
E
L
V
K
F
E
D
K
T
D
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
0
13.3
13.3
N.A.
86.6
86.6
N.A.
26.6
53.3
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
20
20
N.A.
86.6
86.6
N.A.
40
60
33.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
19
0
19
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% C
% Asp:
0
19
10
0
10
64
0
28
10
10
0
0
10
0
0
% D
% Glu:
28
0
0
46
0
10
46
10
37
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
10
0
0
0
0
0
46
28
10
0
10
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
10
10
10
0
0
% H
% Ile:
0
0
37
0
19
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
10
37
0
0
10
0
37
0
0
0
10
37
19
19
55
% K
% Leu:
0
0
0
0
10
10
0
0
0
10
0
0
0
37
0
% L
% Met:
0
0
0
10
0
0
0
0
0
10
19
0
0
0
19
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
19
0
19
10
10
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
10
0
0
46
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
28
0
0
10
37
28
0
10
0
0
28
0
% S
% Thr:
0
10
28
0
0
0
0
0
0
10
0
10
10
0
0
% T
% Val:
37
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
28
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _